![]() "COVID-19 patients with blood group A or AB appear to exhibit a greater disease severity than patients with blood group O or B," found the study, which was published in the same journal, adding that individuals with blood group O were reported to be "less susceptible to SARS-CoV-2 infection." Similar results were found by a Canadian medical study conducted by 14 researchers based on data collected from intensive care unit patients in six metropolitan Vancouver hospitals. The research indicated that individuals with blood types A, B, and AB were also at higher risk of exhibiting thrombosis - the clotting of blood inside a blood vessel - and cardiovascular diseases, which are significant co-occurring conditions among hospitalized COVID-19 patients. "We demonstrate that blood group O is significantly associated with reduced susceptibility to SARS-CoV-2 infection," said the study published Wednesday on Blood Advances, a peer-reviewed medical journal of the American Society of Hematology. The AP is solely responsible for all content.Two medical studies have suggested that people with blood type O may be at lower risk of contracting the novel coronavirus.Ī Danish study, conducted by 11 researchers based on information of 473,654 individuals tested for COVID-19, found that blood group O was associated with a decreased risk of coronavirus infection. The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education. It's in my view well worth publishing and getting out there," but it needs verification in more patients, Valle said. David Valle, director of the Institute of Genetic Medicine at Johns Hopkins University.īottom line: "It's a provocative study. pylori that can cause ulcers and stomach cancer, said Dr. People with Type O are better able to recognize certain proteins as foreign, and that may extend to proteins on virus surfaces, Hari explained.ĭuring the SARS outbreak, which was caused by a genetic cousin of the coronavirus causing the current pandemic, "it was noted that people with O blood type were less likely to get severe disease," he said.īlood type also has been tied to susceptibility to some other infectious diseases, including cholera, recurrent urinary tract infections from E. Mary Horowitz, scientific chief at the Center for International Blood and Marrow Transplant Research. There are four main blood types - A, B, AB and O - and "it's determined by proteins on the surface of your red blood cells," said Dr. Being older or male seems to increase risk, and scientists have been looking at genes as another possible "host factor" that influences disease severity. Many researchers have been hunting for clues as to why some people infected with the coronavirus get very ill and others, less so. Most genetic studies like this are much larger, so it would be important to see if other scientists can look at other groups of patients to see if they find the same links, Topol said. They also tied blood groups to possible risk. Researchers tied variations in six genes to the likelihood of severe disease, including some that could have a role in how vulnerable people are to the virus. The study, involving scientists in Italy, Spain, Denmark, Germany and other countries, compared about 2,000 patients with severe COVID-19 to several thousand other people who were healthy or who had only mild or no symptoms. Eric Topol, head of the Scripps Research Translational Institute in San Diego. it isn't enough of a signal to be sure," said Dr. The evidence of a role for blood type is "tentative. With the new work, "now I believe it," he said. Parameswar Hari, a blood specialist at the Medical College of Wisconsin, said of the report from China. "Most of us discounted it because it was a very crude study," Dr. Newsletter sign-up: Get The COVID-19 Brief sent to your inbox.
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